Hypogonadism is present Prader-Willi syndrome (PWS) is a complex genetic disorder with many manifestations and potential medical and psychiatric complications. It is caused by the lack of expression of genes on the paternally derived chromosomeqq The management of these patients requires an expert and highly specialized multidisciplinary team Prader-Willi syndrome is a complex genetic condition that affects many parts of the body. It is important to know about the general Do’s and Don’ts when living, playing, and working with someone who has PWS so that you can help them manage their feelings and behavior better Prader-Willi syndrome (PWS) is characterized by severe hypotonia, poor appetite, and feeding difficulties in early infancy, followed in early childhood by excessive eating and gradual development of morbid obesity (unless food intake is strictly controlled). Motor milestones and language development are delayed. This Journal-based CME activity is available in print and online as full text HTML and as a PDF that can be viewed and/or printed using Adobe Acrobat Brief Overview of PWS. PWS is a very complex, neurobehavioral, genetic disorder caused by an abnormality on theth chromosome. In infancy, this condition is characterized by weak muscle tone (hypotonia), feeding difficulties, poor growth, and delayed development. Beginning in childhood, affected individuals develop an extreme hunger, which leads to chronic overeating (hyperphagia People with Prader-Willi syndrome generally love life and people but frequently have a difficult time managing themselves when they feel frustrated or anxious. Because of cognitive dysfunction and behavioral problems, adults with PWS might Prader-Willi syndrome (PWS) is characterized by severe hypotonia and feeding dificulties in early infancy, followed in later infancy or early childhood by excessive eating and gradual Prader-Willi syndrome as a model of hypothalamic dysfunction, and provide a comprehensive description of the accumulated knowledge on genetics, pathophysiology, Prader-Willi syndrome (PWS) is a complex, lifelong, life-threatening disorder that causes myriad symptoms including low muscle tone, sensory integration dysfunction, and Method of Participation. Genetic testing is available to confirm the diagnosis. Most of the challenges they face result from Palabras clave: Síndrome de Prader Willi Abstract Prader Willi syndrome is a complex and multisyste-mic genetic disorder with intellectual disability. All individuals have some degree of cognitive impairment.